18 Nov 2009 Update - EACS Conference 2009 Cologne
To see pdf versions of the oral presentations and posters presented at the EACS Conference in Cologne, as well as Jens Lundgren's plenary presentation, please follow this link.A link to the HIV in Europe session will soon be available.
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17 Nov 2009 EACS Conference 2009 Cologne
The next EACS Conference will be 11-14 November, 2009 in Cologne, Germany.Click here for a list of oral presentations and posters to be presented at the conference. Please follow the links below for information about meetings to be held during the conference. EuroSIDA Meetings DAD Meeting HIV-TB Meeting
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30 Oct 2009 HIV in Europe 2009 Stockholm
CHIP is co-chairing the HIV in Europe 2009 Follow-up Meeting, 2nd and 3rd of November 2009 at the Nobel Forum, Karolinska Institute, Stockholm, Sweden.
Follow the seminars from HIV in Europe 2009 Stockholm live at: www.hiveurope.eu
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04 Sep 2009 FLU Studies
INSIGHT is conducting two international observational studies on the pandemic Influenza virus (H1N1v). The studies will open in September 2009. CHIP is coordinating these studies in 11 countries within Europe (Austria, Belgium, Denmark, Estonia, Germany, Lithuania, Norway, Poland, Portugal, Spain and Sweden). read more...
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12 Mar 2009 CROI Final Slides
The final slides from CROI 2009 are now available. To access, please follow the link below.
read more...
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27 Feb 2009 NIH Press Release
IL-2 Immunotherapy Fails to Benefit HIV-Infected Individuals Already Taking Antiretrovirals. Click here to read.
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27 Feb 2009 CROI 2009
Posters and Presentations at CROI 2009 Association between modifiable and non-modifiable risk factors and specific causes of death in the HAART era: Results from the D:A:D study. C Smith, R Weber, S Worm, A Phillips, R Thiebaut, N Friis-Møller, C Pradier, O Kirk, A d'Arminio Monforte, W El Sadr, P Reiss, J Lundgren, C Sabin on behalf of the D:A:D Study Group.Oral 113 KB
Risk of myocardial infarction (MI) in those exposed to specific antiretroviral drugs (ARVs) from the protease (PI), non-nucleoside reverse transcriptase (NNRTI) and nucleos(t)ide reverse transcriptase inhibitor (NRTI) drug classes: the D:A:D Study. JD Lundgren, P Reiss, S W Worm, W El-Sadr, S DeWit, R Weber, A d'Arminio Monforte, O Kirk, E Fontas, F Dabis, M G Law, N Friis-Møller, A N Phillips, C Sabin, on behalf of the D:A:D study group.Oral 115 KB. To watch the presentation, click here. To access the Framingham Risk Calculator, click here .
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01 Dec 2008 Interview med Jens Lundgren i Information
Information bringer i dag, 1. december, interview med Jens Lundgren.
Læs interviewet her
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28 Nov 2008 To ledige stillinger hos CHIP
CHIP søger i øjeblikket en professorsekretær/koordinator og en bioinformatiker. Se nedenstående link for yderligere detaljer.
read more...
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28 Nov 2008 SILCAAT Newsletter No 9
The SILCAAT Newsletter No 9 is now out. Please follow the link to see the newsletter.
read more...
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24 Nov 2008 Forskningsfrihed - artikel i Universitetsavisen
Interview med Jens Lundgren og Signe Worm i Universitetsavisen nr. 14, 21. november 2008 omkring forskningsfrihed.
Læs artiklen her
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21 Nov 2008 European Parliament - Resolution on HIV/AIDS
The European Parliament has on the 19 November 2008 adopted the motion for a resolution on HIV/AIDS: Early Diagnosis and Early Care.
Summary of the debate
The Joint Motion for a Resolution
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18 Nov 2008 Ophæv HIV-loven - præciseringer
På baggrund af pressens omtale af vores forslag om at ophæve "HIV-loven" vil vi gerne præcisere vores holdninger.
Se dette link for at læse mere.
Se desuden også:
Policy Brief: Criminalization of HIV Transmission fra UNAIDS
Criminalisation of HIV Transmission in Europe fra Global Network of People Living with HIV/AIDS Europe and Terrence Higgins Trust.
Criminilization of HIV Transmission and exposure fra IPPF (International Planned Parenthood Federation)
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10 Nov 2008 Presentations at HIV9 Glasgow
Please follow the link to find the poster versions of the HIV9 CHIP presentations.
read more...
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04 Nov 2008 New DHHS Guidelines
The DHHS (Department of Health and Human Services) in the US has on the 3 November 2008 released a new set of guidelines for the use of antiretrovirals in HIV-1-infected adults and adolencents. To see the guidelines please follow this link
read more...
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05 Sep 2008 EuroSIDA article No. 100!
EuroSIDA articel No. 100 was accepted for press this week!
read more...
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05 Sep 2008 Two SMART & SMART/DAD articles published
This week the final report on SMART is published as lead article in Annals of Internal Medicine. Additionally, also as lead article this week the follow-up story to Abacavir is published in AIDS.
read more...
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19 Aug 2008 XVII International AIDS Conference in Mexico City
Jens Lundgren made a presentation on Thursday August 7th 2008 on data from the SMART trial providing further evidence that abacavir (Ziagen) may be associated with a higher rate of cardiovascular events.
The presentation can be found here
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09 Jul 2008 D:A:D Summer Newsletter
The D:A:D Summer Newsletter is out and can be found following this link
read more...
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09 Jul 2008 EuroSIDA Summer Newsletter
The EuroSIDA Summer Newsletter is out now. Please follow this link to read it
read more...
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17 Jun 2008 HIV Drug Resistance Workshop
Two posters were presented at the XVII International HIV Drug Resistance Workshop held in Sitges June 10-14, 2008. To see the posters please follow the link below.
read more...
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02 Apr 2008 D:A:D publication in The Lancet
The article "Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration" is published online today in The Lancet. Please follow this link http://www.thelancet.com/journals/eop
To see D:A:D position statement, please follow the link below
read more...
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01 Apr 2008 Signal Report from Uppsala Monitoring Centre
The Uppsala Monitoring Centre (A WHO Collaborative Centre; http://www.who-umc.org/DynPage.aspx) has recently released a signal report from May 2005 detecting a signal associating abacavir with increased risk of myocardial infarction. The report can be downloaded from their website by use of the following link: http://www.who-umc.org/graphics/15962.pdf.
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26 Mar 2008 Ledig stilling hos CHIP
Der er i øjeblikket et ledig stilling som Personlig Assistent/sekretær hos CHIP. For yderligere information følg nedenstående link.
read more...
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04 Mar 2008 INSIGHT Newsletter
The INSIGHT newsletter for February 2008 can be found following the link below.
read more...
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22 Feb 2008 ESPRIT/SILCAAT Newsletter
To read the latest ESPRIT/SILCAAT newsletter from 22 February 2008 please follow the link below
read more...
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04 Feb 2008 D:A:D position statement
In connection with the presentation at CROI 2008 of the D:A:D poster with the title “Recent Use of Abacavir and Didanosine, but not of Thymidine Analogues, Is Associated with Risk of Myocardial Infarction”(poster No. 957c) the D:A:D steering committee has released a position statement.
To read the position statement, please follow this link
To see the poster, please follow this link
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04 Feb 2008 Posters presented at CROI 2008
The posters presented at CROI 2008 can be found on the CHIP website the day they are presented at the conference. Please follow the link below
read more...
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31 Jan 2008 STALWART Newsletter No. 3
The third STALWART newsletter is now out. To find the newsletter please follow the link below
read more...
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21 Jan 2008 Investigator meeting at CROI
An INSIGHT/SILCAAT Joint Scientific Session will be held on Sunday, 3 February 2008 in Boston in conjunction with the Conference on Retroviruses and Opportunistic Infections (CROI). Deadline for registration is 25 January 2008.
For further details, please follow the link below.
read more...
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02 Jan 2008 CHIP New Years Letter
The CHIP New Years Letter is now available, and can be found here.
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14 Dec 2007 EuroCOORD/COHERE meeting at CROI
A EuroCOORD/COHERE meeting will be held in connection with the 15th CROI Conference in Boston. For further details please follow the link below.
read more...
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13 Dec 2007 D:A:D SC meeting at CROI
A D:A:D Steering Committee meeting will be held in connection with the 15th CROI conference in Boston. Please follow the link for further details.
read more...
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16 Nov 2007 Tiltrædelsesforedrag 30. november
Professor Jens D. Lundgren vil den 30. november holde sin tiltrædelsesforelæsning i Haderup Auditoriet på Panum samtidig vil der være indvielse af CHIPs nye lokaler.
Se invitationen her
On the 30 November Professor Jens D. Lundgren will hold his inaugural speech in the Haderup Auditorium at the Panum Institute and the opening of CHIPs new premises will take place
Invitation in English here
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01 Nov 2007 CHIP Report 2006/2007
The CHIP report for 2006/2007 can be downloaded following the link below. To receive a hard copy please contact us at chip@cphiv.dk
read more...
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24 Oct 2007 EACS Posters
Please use link below to download posters presented at the 11th European AIDS Conference in Madrid, 24-27 October 2007
read more...
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11 Oct 2007 HIV in Europe
HIV in Europe 2007: Working together for optimal testing and earlier care
University of Copenhagen (represented by Copenhagen HIV Programme)and AIDS Action Europe with technical assistance from WHO Europe have come together to organise a pan-European conference entitled "HIV in Europe 2007: Working together for optimal testing and earlier care" in anticipation of World AIDS Day 2007. For further details on the conference, please follow this link.
read more...
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28 Sep 2007 STALWART Newsletter
The second STALWART newsletter is now out. Please follow the link to read the newsletter
read more...
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20 Sep 2007 EuroSIDA Newsletter
The EuroSIDA newsletter for the Fall 2007 is now out. Please follow the link to find the newsletter
read more...
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29 Aug 2007 EuroSIDA investigator meeting
An EuroSIDA investigator meeting will be held in connection with the 11th European AIDS Conference in Madrid October 24-27, 2007. Please follow link for more details.
read more...
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28 Aug 2007 Upcoming INSIGHT/SILCAAT meeting
A joint INSIGHT/SILCAAT investigator meeting will be held in connection with the 11th European AIDS Conference in Madrid October 24-27, 2007. Please follow link for more details.
read more...
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20 Aug 2007 D:A:D SC meeting
A D:A:D meeting for Steering Committee members and Database Managers will be held 2 October 2007. Please follow link for more details.
read more...
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16 Aug 2007 INSIGHT Newsletter
INSIGHT newsletter for July 2007 can be found following the link below
read more...
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19 Jul 2007 EuroSIDA publication in The Lancet
The EuroSIDA article "Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study" has been published today online in The Lancet
read more...
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25 Jun 2007 INSIGHT/SILCAAT Joint Scientific Session
The meeting is scheduled to precede the opening of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention. Please follow link for more details and registration
read more...
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20 Jun 2007 SMART Newsletter
SMART ICC newsletter for June 2007 is now out. Please follow link for further details
read more...
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13 Jun 2007 XVI International HIV Drug Resistance Workshop
Please find the 4 posters presented at the XVI International HIV Drug Resistance Workshop in Barbados by following the link below
read more...
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23 May 2007 Two new EuroSIDA publications
Two recent EuroSIDA publications in AIDS this month. Please follow the link below
read more...
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26 Apr 2007 D:A:D article in NEJM
The article `Class of Antiretroviral Drugs and the Risk of Myocardial Infarction´ is published today in the New England Journal of Medicine. Please follow the link below for further information and see press release (in Danish)
read more...
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20 Apr 2007 EACS 5th Advanced HIV Course
The European AIDS Clinical Society / EACS announces the 5th Advanced HIV Course Management of HIV Treatment. Please follow the link below for further details.
read more...
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30 Mar 2007 Drug Resistance Conference in Cascais
Please go to the link below to see poster from the 5th European HIV Drug Resistance Workshop in Cascais, Portugal
read more...
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29 Mar 2007 SILCAAT Recycling Status
It is now possible to follow the recycling status for each SILCAAT site in the Copenhagen region under SILCAAT at the CHIP website. The status will be updated every week. Please follow the status of your own country carefully. Please follow the link below.
read more...
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28 Mar 2007 ESPRIT Recycling Status
It is now possible to follow the recycling status for each ESPRIT site in the Copenhagen region under ESPRIT at the CHIP website. The status will be updated every week. Please follow the status of your own country carefully.
Please follow the link below.
read more...
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13 Mar 2007 INSIGHT website
The INSIGHT website is now up and running and the old websites have been closed down as of 12 March 2007. New passwords have been sent to all sites. If you for some reason has not received the new password, please contact CHIP. To go to the INSIGHT website please use the link below
read more...
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27 Feb 2007 CROI Posters
The six posters from the CROI conference in Los Angeles, February 25-28 can be downloaded and printed if you follow the link below.
read more...
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21 Feb 2007 SILCAAT Newsletter No. 7
The SILCAAT ICC Newsletter No.7 is out now, please follow link for details.
read more...
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09 Feb 2007 DAD meeting at CROI
A DAD steering committee meeting will be held in connection with the CROI conference. Please follow this link for further details.
read more...
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01 Feb 2007 Investigator meeting at CROI
An INSIGHT/SILCAAT investigator meeting will be held in connection with the CROI Conference in Los Angeles. Please follow link for further details
read more...
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30 Jan 2007 ESPRIT newsletter No. 13
The 13th ESPRIT newsletter is now out, please follow the link for further details
read more...
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15 Jan 2007 Article in BMJ on When to Start
An editorial was published in BMJ 13 January with the title When should antiretroviral therapy for HIV be started?
This question was also commented in the Washington Post on Sunday 7th January 2007 http://www.washingtonpost.com/wp-dyn/content/article/2007/01/06/AR2007010601097.html?referrer=emailarticle
Please follow this link to find the article
read more...
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30 Nov 2006 SMART publication in NEJM
The publication from the SMART study "CD4+ Count–Guided Interruption of Antiretroviral Treatment" is published in the New England Journal on the 30 November 2006 together with an editorial.
Please follow the links below to see the article and editorial:
Article: http://content.nejm.org/cgi/content/short/355/22/2283
Editorial: http://content.nejm.org/cgi/content/short/355/22/2359
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24 Nov 2006 CROI 2007 presentations
At the CROI Conference taking place in Los Angeles in February 2007, 4 abstract from the DAD study and 2 from the EuroSIDA study have been accepted. The DAD study will have 1 oral and 3 poster presentations and the EuroSIDA study will have 2 posters.
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21 Aug 2006 New D:A:D publication
The D:A:D article 'Liver-Related Deaths in Persons Infected With the Human Immunodeficiency Virus: The D:A:D Study' is out now in Archives of Internal Medicine. Please follow the link below to see the abstract.
read more...
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14 Jul 2006 The INSIGHT Network
The INSIGHT leadership application has been viewed favorable by The National Institute of Allergy and Infectious Diseases (NIAID) and a grant has been received to support the "International Network for Strategic Initiatives in Global HIV Trial (INSIGHT)".
INSIGHT (International Network for Strategic Initiatives in Global HIV Trial) is a merger of two existing NIAID-funded clinical trials research groups, ESPRIT (Evaluation of Subcutaneous Proleukin in a Randomized International Trial) and the CPCRA (Terry Bain Community Programs for Clinical Research on AIDS). Leadership for ESPRIT, SMART and STALWART will be assumed by the new INSIGHT network.
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07 Jul 2006 STALWART Newsletter
The first STALWART newsletter is now ready.
Please follow the link to find it.
read more...
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07 Jul 2006 ESPRIT newsletter
The 12th ESPRIT newsletter is now out.
Please follow the link to find the newsletter
read more...
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26 Jun 2006 EuroSIDA newsletter
The EuroSIDA summer newsletter for 2006 is now out. Please find it under the link below.
read more...
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03 Apr 2006 DAD publication in HIV medicine
The DAD article "The use of the Framingham equation to predict myocardial infarction in HIV infected patients" is out now in HIV medicine
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15 Feb 2006 EuroSIDA Spring Newsletter
The EuroSIDA Spring 2006 newsletter is now out. Please use link to go to newsletter.
read more...
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08 Feb 2006 CROI 2006 Presentations
Please follow the link to see the oral presentations and posters presented at the CROI 2006.
read more...
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18 Jan 2006 SMART study - news release
NIH today announced that enrollment into the SMART trial has been stopped. Enrollment was stopped because those patients receiving episodic therapy had twice the risk of disease progression (the development of clinical AIDS or death), the major outcome of the study.
NIAID made the decision to halt enrollment in collaboration with the study’s Executive Committee and following a recommendation received from an independent Data and Safety Monitoring Board (DSMB). The DSMB, charged with regularly evaluating data and safety issues during the multi-year trial, conducted a review of the interim study data in early January.
For more information, please see link below.
read more...
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22 Nov 2005 Presentations at EACS in Dublin
CHIP was represented with four posters and four oral presentations at the EACS in Dublin 17-20 November 2005. Please press the link to see titles and posters.
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26 Oct 2005 Two articles from the D:A:D study
Two articles from the D:A:D study are in press, and will appear shortly in Antiviral Therapy and HIV Medicine
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12 Oct 2005 EuroSIDA newsletter Fall 2005
The EuroSIDA newsletter Fall 2005 can now be found at the website, please use the link below
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11 Oct 2005 DAD newsletter
The latest DAD newsletter, no. 9 October 2005, is now out and can be found by using the link below
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23 Aug 2005 EuroSIDA publications
Two more EuroSIDA articles have been accepted for publication in AIDS and Antiviral Therapy repectively.
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23 Aug 2005 EuroSIDA newsletter Summer 2005
The EuroSIDA newsletter for the summer 2005 is now available. Please press the link to go to the newsletter.
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05 Aug 2005 4000th patient in SMART!
Today the 4000th patient was enrolled in SMART! This means that 2/3rds have been enrolled - congratulations to all!
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29 Jul 2005 SMART RCC Newsletter No. 5
The SMART RCC Newsletter No. 5 is today being distributed. The RCC Newsletter is electronically available.
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12 Jul 2005 Rio - Joined Investigators Meeting
A Joint Scientific Session for SMART, SILCAAT, ESPRIT, and STALWART investigators is planned for Sunday afternoon, 24 July 2005 from 13:00-17:00. For furher information please press the link.
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11 Jul 2005 INSIGHT network application
The INSIGHT application has now been completed and submitted to the NIH.
Thank you very much to everybody that has been supporting this application process with help and information.
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27 Jun 2005 SMART site open in Lituania
The Lithuanian AIDS Center in Lithuania was opened last week and is now ready to enroll patients - congratulations!
In the Copenhagen Region we have now enrolled 350 patients into SMART.
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26 Apr 2005 EuroSIDA Newsletter April 2005
The latest EuroSIDA newsletter of April 2005 is now available on the website, please use the link below for access
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25 Apr 2005 CHIP annual report 2004
The CHIP annual report 2004 is ready and can be found on the website, please use the link below
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15 Apr 2005 SMART Patient no. 100 in Germany!
SMART patient no. 100 was randomised yesterday
in Germany at the J.W Goethe University Hospital. Congratulations!
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13 Apr 2005 ESPRIT/SILCAAT RCC Newsletter
A combined ESPRIT (no. 9) and SILCAAT (no 5) newsletter is now available on the website. The main topic in this newsletter is the IL-2 re-cycling. Please use the link for further information.
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05 Mar 2005 Patient No. 3000 in SMART
Today patient No. 3000 was randomised into the SMART study bringing recruitment half way to the planned inclusion of 6000 patients.
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24 Feb 2005 CROI 2005 Posters
2 DAD posters and 4 EuroSIDA posters are presented at CROI 2005.
Please use the link below to go to the website from where you will be able to down-load PDF versions of the posters.
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17 Feb 2005 DAD 8th newsletter
The 8th DAD newsletter is now available on the website.
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16 Feb 2005 DAD documents updated
The DAD study documents have been updated. It is possible to download the new versions as PDF files from the website.
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16 Feb 2005 Updated CoDe documents
The pilot has been completed, and we are happy to launch the
final CoDe (Coding of Death in HIV) documents.
Please find information about CoDe and the final CoDe documents on the website.
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19 Jan 2005 EuroSIDA at CROI 2005
Four EuroSIDA abstracts have been accepted for the 12th Conference on Retroviruses and Opportunistic Infections that will take place in Boston, February 2005.
For further information on these abstracts and DAD abstracts to be presented at CROI, please see links below.
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19 Jan 2005 CHIP Presentations at CROI 2005
Jens Lundgren has been invited to speak at the 12th Conference on Retroviruses and Opportunistic Infections that will take place in Boston, February 2005. Please see link below for further information
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19 Jan 2005 DAD Presentations at CROI 2005
Three DAD abstracts (1 oral and 2 posters) have been accepted for the 12th Conference on Retroviruses and Opportunistic Infections that will take place in Boston, February 2005.
Please see link below for further information
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04 Jan 2005 DAD SC meeting at CROI
A DAD steering committee meeting will be held in connection with CROI on February 5th.
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22 Dec 2004 EuroSIDA publication list updated
We have updated the publication list as several articles now have been published.
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09 Dec 2004 EACS Exchange Programme
The EACS Medical Exchange Programme for Young HIV Physicians applocation deadline for 2005 is the 16 January 2005. For further information please see the EACS website.
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06 Dec 2004 SMART RCC Newsletter No. 3
The SMART RCC Newsletter No. 3 is today being distributed together with the SMART Provider Update Newsletter to all sites. The RCC Newsletter is electronically available.
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06 Dec 2004 Shipping samples to CHIP
The guidelines for shipping samples have changed slightly - there is a requirement for a new label to be added to the shipping boxes used. (IATA packaging instruction 650).
Our guidelines have been updated - please see Revised packing instructions
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02 Dec 2004 DAD Steering Committee meeting
The next DAD Steering Committee meeting will take place during CROI
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16 Nov 2004 New Ph.D. dissertation
CHIP is happy to announce that Nina Friis-Moeller, MD has obtained a Ph.D. from the University of Copenhagen by succesfully defending her dissertation "Cardiovascular Adverse Effects of Antiretroviral Therapy" on November 12th.
Interested parties can obtain a copy of the dissertation by contacting CHIP, or download the pdf document.
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08 Nov 2004 CoDe
The CoDe (Coding of Death in HIV) project is now being initiated.
A pilot is taking place from Nov 5th - Dec 15th
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29 Sep 2004 EuroSIDA Newsletter
The latest newletter from the EuroSIDA study is available.
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26 Jul 2004 XV AIDS Conference in Bangkok
Abstracts from the XV International AIDS Conference in Bangkok are now available.
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09 Jun 2004 New EuroSIDA publications
The EuroSIDA publication list has been updated with 5 new publications.
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26 May 2004 EU Directive effective
On May 1, 2004, EU Directive 2001/20/EC became effective in EU membership countries. A unique EudraCT number must now identify all clinical trials. Please contact CHIP for further information.
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04 May 2004 SMART patient no. 1 enrolled
The first SMART patient in the Copenhagen region was randomised earlier today by our colleagues at St. Pierre Hospital in Brussels. Congratulations!!
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19 Apr 2004 CHIP Annual Report
Below please find a pdf.-version of the Copenhagen HIV Programme Annual Report 2003 containing information on major events, progress for clinical trials and cohort collaborations.
Please contact the CHIP office for hard copies (email:chip@cphiv.dk).
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01 Apr 2004 SILCAAT Newletter
The first SILCAAT RCC newsletter for 2004 has been distributed to all sites via email and will also be sent via regular mail, please find link to the newsletter below.
SILCAAT Newsletter
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01 Apr 2004 ESPRIT Newsletter
The first ESPRIT RCC newsletter for 2004 has been distributed to all sites via email and regular mail, please find link to the newsletter below.
ESPRIT Newsletter
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01 Apr 2004 SMART Newsletter
The first SMART newsletter will be distributed to all sites via email and regular mail, please find link to the newsletter below.
SMART Newsletter
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10 Feb 2004 Posters presented at CROI 2004
The following posters were presented at CROI:
D:A:D study: Poster # 737
"Cardio- and Cerebrovascular Events (CVE) and Predicted Rates of Myocardial Infarction (MI) in the D:A:D Study"
Colate study: Poster #549
"Week 48 Analysis of a Phase IV, Randomised, Open-label, Multi-centre Trial to Evaluate Safety and Efficacy of Continued Lamivudine Twice Daily Versus Discontinuation of Lamivudine in HIV-1 Infected Adults With Virological Failure on
Ongoing Combination Treatments Containing Lamivudine: The COLATE Trial"
MaxCmin2 study: Poster #Lipid 720
"Lipid Profiles of Patients Enrolled in the MaxCmin2 Trial: A Randomized, Open-Label, Multicenter Comparative Trial Evaluating the Safety and Efficacy of lopinavir/ritonavir (LPV/r; 400/100 mg bid) versus saquinavir/ritonavir (SAQ/r; 1000/100 mg bid)"
MaxCmin study: Poster # 619b
"The Role of Genetic Polymorphisms of the MDR1 (ABCB1) Gene in the MaxCmin1 Study"
EuroSIDA study: Poster
"Hepatitis B (HBV) and Hepatitis C (HCV) in the EuroSIDA Cohort: Prevalence
and Impact on Mortality, AIDS Progression and Response to HAART"
EuroSIDA study: Poster #554
"Time to Triple Drug Class Failure after Initiation of HAART"
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09 Feb 2004 EuroSIDA Newsletter
The first newsletter for 2004 has been distributed to all sites, please find link to the newsletter below.
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06 Feb 2004 Oral presentation at CROI
D:A:D Study: Abstract # N-46;
Session: Complications of HIV Infection and Antiretroviral Therapy (Tuesday February 10th , 10 am - 12:30 pm)
An oral presentation on analyses of blood pressure changes and hypertension (R. Thiebaut et al)
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02 Feb 2004 DAD Newsletter February 2004
The DAD newsletter of February 2004 is now on the website
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01 Dec 2003 UNAIDS - Annual update
The annual AIDS epidemic update reports on the latest developments in the global HIV/AIDS epidemic. With maps and regional summaries, the 2003 edition provides the most recent estimates of the epidemics scope and human toll, explores new trends in the epidemics evolution, and features a special section examining stigma and discrimination.
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19 Nov 2003 D:A:D Position Statement
A Position Statement on Combination Antiretroviral
Therapy and the Risk of Myocardial Infarction has been released on November 19, 2003.
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13 Nov 2003 Links added
New pages on links for various ressources in relation to clinical trials has been added.
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06 Nov 2003 SILCAAT Position Statement
A Position Statement on provision of IL-2 to control patients has been released on October 17, 2003 by the Scientific Committee.
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31 Oct 2003 SMART Presentation available
The presentation from the recent Investigators meeting in Warsaw is now available on our web-site.
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27 Oct 2003 EuroSIDA booklet
A presentation of abstracts from the EuroSIDA Study has just been published under the title "Tracking HIV/AIDS across Europe 2003".
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23 Oct 2003 EuroSIDA in Warsaw
Below please find a link for the date, time and location of the EuroSIDA presentations taking place at the EACS conference in Warsaw next week;
5 oral presentations
2 poster presentations
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22 Oct 2003 MaxCmin in Warsaw
Below please find a link for the date, time and location of the three MaxCmin oral presentations taking place at the EACS conference in Warsaw next week.
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07 Oct 2003 ESPRIT Freq. Raised Issues No 6
A new volume of Frequently Raised Issues has been posted to the ESPRIT investigators web-site adn will be distributed to site in ESPRIT in the next days.
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25 Sep 2003 ART Cohort Collaboration in Lancet
An article by Egger et al has been published in Lancet:
Prognostic importance of initial response in HIV-1 infected patients
starting potent antiretroviral therapy: analysis of prospective studies.
Lancet. 2003 Aug 30;362(9385):679-86.
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09 Sep 2003 EuroSIDA publication list updated
The publicationlist has been updated with the latest refences to the article:
Virological rebound after suppression on highly active antiretroviral therapy by Amanda Mocroft et al. in AIDS
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27 Aug 2003 MaxCmin1 article in JID
An article on results from the MaxCmin1 trial "Randomized Trial to Evaluate Indinavir/Ritonavir versus Saquinavir/Ritonavir in Human Immunodeficiency Virus Type 1Infected Patients: The MaxCmin1 Trial" has just been published in The Journal of Infectious Diseases (2003;188:635-642)
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23 Jul 2003 First sites transferred in SILCAAT
The two sites in Belgium, C.H.U. St. Pierre, Brussels and Institute for Tropical Medicine, Antwerp have now transferred into version 4.0 of the SILCAAT protocol.
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04 Jul 2003 EuroSIDA article in Lancet
Today an article by Amanda Mocroft et al. was published in the Lancet, which found a sustained effect of anti-HIV combination treatment since it was introduced in Europe in 1996.
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25 Jun 2003 HIV Data Exchange Protocol
Information about the HICDEP - HIV Collaboration Data Exchange Protocol has been added to our web-site.
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16 Jun 2003 ESPRIT/SILCAAT Scientific Session
ESPRIT AND SILCAAT: Scientific session on Sunday, July 13 from 13.00 to 16.00 chaired by Drs. Fauci and Kazatchkine
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01 Jun 2003 EuroSIDA Newletter June 2003
Dear colleagues.Publications: Since last newsletter, three paper have been published: one of virological deadlock in Antiviral Therapy with Alessandro Cozzi-Lepri as first author, one on the influence of gender on the response to HAART in JAIDS with Antonia Moore as first author, and finally the DAD baseline paper in AIDS with Nina Friis-Møller as first author. In addition, three papers have been accepted for publication: one on changes in mortality and morbidity with Amanda Mocroft as first author will appear in Lancet, another also with Amanda as first author analysing the virological rebound in AIDS and one on low CD4 response to HAART despite undetectable viral load headed by Eric Florence from Antwerp has been accepted by HIV Medicine.
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31 May 2003 ESPRIT Randomisation closed!
Dear colleagues, we finished enrollment on Friday with 4,150 patients randomized. If all goes as planned, we have about 50,000 follow-up visits to go and we will complete our work.
Congratulations to all!
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22 May 2003 SILCAAT RCC Newsletter No 2
Dear colleagues and collaborators in SILCAAT.This is the second SILCAAT Newsletter issued by the Copenhagen RCC, Copenhagen HIV Programme (CHIP). We have now finished the first round of discussions with investigators in the region on the feasibility of continuing the trial until its scientifically driven completion. These discussions have been conducted in a collaborative and collegial atmosphere. We are happy to say that it will indeed be possible to continue the trial, and similar messages are coming from other regions as well. As mentioned in the previous newsletter, the challenge will be to continue to recycle patients randomised to receive IL-2 and continue to follow closely all patients randomised for signs of clinical disease progression – the primary endpoint of the trial. Thanks to all of you who are still working hard to make this study a success.
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15 May 2003 New DAD publication
Cardiovascular risk factors in HIV patients - association with antiretroviral therapy Results from the DAD Study.
Friis-Møller N, Weber R, Reiss P, Thiebaut R, Kirk O, dArminio MA et al.
AIDS 2003; 17(8):1179-1193
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24 Apr 2003 ESPRIT RCC Newsletter No 6
Dear ESPRIT investigator,
On the 15th of April 2003, the ESPRIT trial reached the enrolment target of 4,000 patients making this trial the largest randomised HIV trial to date. Congratulations and thank you very much to all staff that has contributed to this remarkable achievement.
According to the decision made during the last International Steering Committee meeting randomisation will continue for 45 days after enrolment of patient No. 4,000 to ensure that patients undergoing screening will have an opportunity to participate in the trial. Randomisation will close at midnight (CET) of the 30th of May 2003.
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